An Overview of U.S. Occupational Employment and Wages in 2011

A substantial share of U.S. employment in May 2011 was concentrated in a relatively small number of occupations. Just 10 occupations made up more than 20 percent of total employment, and the 20 largest occupations made up nearly one-third of employment—more than 41 million jobs. Most of these large occupations had below-average wages, as did most of the occupations with the highest job gains and losses between May 2007 and May 2011. Growth in the healthcare industry helped to shape employment gains in individual occupations, while construction and production occupations were concentrated in shrinking industries. Although the overall occupational structure of the U.S. economy generally reflected that of the private sector, education and protective service occupations were more prevalent in the public sector, particularly in local government. This issue of BEYOND THE NUMBERS uses data from the Occupational Employment Statistics (OES) program to provide an overview of U.S. occupational employment and wages in May 2011. The first section presents employment and wage data for wage and salary workers in the largest U.S. occupations and selected occupational groups. The subsequent sections highlight occupations with the highest job gains and losses between May 2007 and May 2011, occupations prevalent in growing and shrinking industries, and occupational employment comparisons between the public and private sector

Enabling learning through technology: Some institutional imperatives

This paper considers the importance of the institution as the dynamic interpretative element on which will depend the successful integration of the learning technology developed through our national initiatives into the academic curricula of Higher‐Education institutions. Based on our experience of working on teaching technology programmes, within the framework of national and institutional initiatives, it is evident that the establishment of an institutional strategy, and its implementation in a supporting university‐wide programme of staff development and training, together with strong commitment at the senior managerial level, are imperatives which determine the successful integration of learning technology within academic institutions

Crop protection in organic agriculture - a simple matter?

This report was presented at the UK Organic Research 2002 Conference. Crop protection strategies in organic agriculture and horticulture aim to prevent pest, disease and weed problems through optimisation of the cropping system as a whole. Choice of crops and varieties within the rotation and use of appropriate husbandry practices are critical to the success of the system and direct curative action against pests and diseases is rarely necessary. Research is urgently needed to determine strategies for control of key pests and diseases in organic systems if UK organic agriculture is to expand to meet increasing consumer demand. This paper describes current prevention and control strategies for pests, diseases and weeds in UK organic agriculture and identifies problems that are currently limiting expansion of the industry

An investigation into the relationship between preceding break crops and weed populations in barley crops in organic ley/arable rotations

This report was presented at the UK Organic Research 2002 Conference. The relationship between weed populations and cereal crops following nine organic break crops was investigated in field trials in Warwickshire, Aberdeenshire and Ceredigion in 2001. Weed biodiversity was high on all sites and varied between sites in terms of species present. Severity of weed infestation differed significantly between sites and between cereals following different break crops. The impact of break crop species on the incidence and severity of the weed burden in the following cereal is discussed in relation to the field trials at the three sites

Effects of composting manures and other organic wastes on soil processes and pest and disease interactions

Introduction Composts and manures are of major importance in providing fertility in organic farming systems, since synthetic fertilisers are prohibited. It is understood that composts have radically different nutrient release characteristics to those of uncomposted materials and manures, and it is believed that composting increases the beneficial effects of organic materials on soil health, soil quality, soil fertility and nutrient use efficiency. It has also been shown that some plant pests and diseases are suppressed through the application of composts and compost extracts to soils. There is considerable potential to use a wider range of feedstocks from on and off-farm sources and to improve the composting process and compost/manure application techniques. This review of scientific work to date was urgently required to help determine key research priorities to achieve this potential (Defra project OF0313). Project aims 1.To document the current standards, regulations and legislation relevant to recycling, compost/manure preparation and application and to review common UK practices relating to the preparation and application of uncomposted materials, manures, composts and compost extracts. 2. To review current scientific knowledge (from the literature) of the effects of different composting processes on chemical and biological parameters in the finished compost or compost extract. 3. To review (from the literature) the effects of uncomposted materials, manures and composts on soil health and quality, soil fertility and crop development and nutrition. 4. To review (from the literature) the effects of uncomposted materials, manures, composts and compost extracts on pest and disease incidence and severity in agricultural and horticultural crops. 5. To outline a proposed strategy for research which seeks to develop composting systems and compost/manure application protocols with a view to optimising soil fertility management and pest and disease control in organic agriculture and horticulture. Objective 1 - The current standards, regulations and legislation relevant to recycling, compost/manure preparation and application are documented in detail in the full report on Objective 1 (Appendix 2). Manures and uncomposted plant materials (e.g. green manures) are commonly used on UK organic farms. True composts (defined in the glossary, Appendix 1) are rarely prepared on UK organic farms, although there is increasing interest in their use, particularly on farms producing high value horticultural crops. An increasing number of companies are producing (or are interested in producing) composts suitable for use on organic farms as soil amendments or growing media. Objective 2 - The effects of different composting processes on chemical and biological parameters in the finished compost or compost extract are reviewed in detail in the full report on Objective 2 (Appendix 3). A short version of this review appears on pages 7-10 of this report. Objective 3 - The effects of uncomposted materials, manures and composts on soil health and quality, soil fertility and crop development and nutrition are reviewed in detail in the full report on Objective 3 (Appendix 4). A short version of this review appears on pages 10-13 of this report. Objective 4 - The effects of uncomposted materials, manures, composts and compost extracts on pest and disease incidence and severity in agricultural and horticultural crops are reviewed in detail in the full report on Objective 4 (Appendix 5). A short version of this review appears on pages 13-17 of this report. Objective 5 - A proposed strategy for research was outlined which seeks to develop composting systems and compost/manure application protocols with a view to optimising soil fertility management and pest/disease control in organic agriculture/horticulture Organic farming systems are by nature holistic. In other words, they function as a whole and all aspects of the system are interdependent on many other aspects of the system. It is essential therefore that research which is carried out to optimise the use of uncomposted plant residues, composts, manures and compost extracts is interdisciplinary; that is it must be carried out with reference to the organic farming system as a whole and not just a single aspect of it. Technology transfer and knowledge transfer are key elements to the proposed strategy for research. Seminars and conferences, farm walks, demonstration farms and a wide range of publishing formats must be used to ensure that end users have full access to the results of research carried out in the UK and abroad. The amount of information which is available for dissemination to those who wish to make or use composts will naturally depend on the amount of relevant research and development work which is going on in the UK, Europe and worldwide

Guest editorial : girls' and women's participation in STEM : past lessons and possible futures

Although the presence of women and girls in many Science, Technology, Engineering, and Mathematics (STEM) fields has increased in recent decades, women remain underrepresented in STEM in comparison to men (Watt, 2010). Structures and processes that compromise women and girls’ entry to and advancement in STEM fields (e.g., cultural messages, see Halpern, Benbow, Geary, Gur, Hyde & Gernsbacher, 2007) appear to per sist despite historical evidence of female ability and competence in STEM (OECD, 2015). The current Special Issue 'Girls' and women's participation in STEM: Past lessons and possible futures’, foregrounds the need for vigilance in ensuring equitable STEM opportunities for women and girls, in the light of historical events. However, the Special Issue also reports evidence and approaches that offer forward momentum in addressing inequitable opportunity and promoting futures for women and girls, in a diversity of STEM fields

HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease

DNA damage contributes to brain aging and neurodegenerative diseases. However, the factors stimulating DNA repair to stave off functional decline remain obscure. We show that HDAC1 modulates OGG1-initated 8-oxoguanine (8-oxoG) repair in the brain. HDAC1-deficient mice display age-associated DNA damage accumulation and cognitive impairment. HDAC1 stimulates OGG1, a DNA glycosylase known to remove 8-oxoG lesions that are associated with transcriptional repression. HDAC1 deficiency causes impaired OGG1 activity, 8-oxoG accumulation at the promoters of genes critical for brain function, and transcriptional repression. Moreover, we observe elevated 8-oxoG along with reduced HDAC1 activity and downregulation of a similar gene set in the 5XFAD mouse model of Alzheimer’s disease. Notably, pharmacological activation of HDAC1 alleviates the deleterious effects of 8-oxoG in aged wild-type and 5XFAD mice. Our work uncovers important roles for HDAC1 in 8-oxoG repair and highlights the therapeutic potential of HDAC1 activation to counter functional decline in brain aging and neurodegeneration

HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease

DNA damage contributes to brain aging and neurodegenerative diseases. However, the factors stimulating DNA repair to stave off functional decline remain obscure. We show that HDAC1 modulates OGG1-initated 8-oxoguanine (8-oxoG) repair in the brain. HDAC1-deficient mice display age-associated DNA damage accumulation and cognitive impairment. HDAC1 stimulates OGG1, a DNA glycosylase known to remove 8-oxoG lesions that are associated with transcriptional repression. HDAC1 deficiency causes impaired OGG1 activity, 8-oxoG accumulation at the promoters of genes critical for brain function, and transcriptional repression. Moreover, we observe elevated 8-oxoG along with reduced HDAC1 activity and downregulation of a similar gene set in the 5XFAD mouse model of Alzheimer’s disease. Notably, pharmacological activation of HDAC1 alleviates the deleterious effects of 8-oxoG in aged wild-type and 5XFAD mice. Our work uncovers important roles for HDAC1 in 8-oxoG repair and highlights the therapeutic potential of HDAC1 activation to counter functional decline in brain aging and neurodegeneration